Tags: Protein.
V-type proton ATPase subunit S1 is an enzyme that in humans is encoded by the ATP6AP1 gene.This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is composed of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain.