Tags: Protein.
ATP2A2 is an ATPase associated with Darier’s disease and Acrokeratosis verruciformis.This gene encodes one of the SERCA Ca(2+)-ATPases which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen and is involved in calcium sequestration associated with muscular excitation and contraction.