Tags: Protein.
ClpS is an N-recognin in the N-end rule pathway. ClpS interacts with protein substrates that have a bulky hydrophobic residue (leucine phenylalanine tyrosine and tryptophan) at the N-temrinus. The protein substrate is then degraded by the ClpAP protease. In molecular biology the ATP-dependent Clp protease adaptor protein ClpS is a bacterial protein. In the bacterial cytosol ATP-dependent protein degradation is performed by several different chaperone-protease pairs including ClpAP.
