Tags: Enzyme.
Aspergillus nuclease S1 is an endonuclease enzyme derived from Aspergillus oryzae that splits single-stranded DNA (ssDNA) and RNA into oligo- or mononucleotides. This enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5′-phosphomononucleotide and 5′-phosphooligonucleotide end-productsAlthough its primary substrate is single-stranded it can also occasionally introduce single-stranded breaks in double-stranded DNA or RNA or DNA-RNA hybrids.