Tags: Protein.
The ARNT gene encodes the aryl hydrocarbon receptor nuclear translocator protein that forms a complex with ligand-bound aryl hydrocarbon receptor (AhR) and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF1). A t(1;12)(q21;p13) translocation which results in a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia.