Tags: Protein.
Rho guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the ARHGEF1 gene.Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene but the full-length nature of some variants has not been defined.