Tags: Chemical Compound, Chemical Substance.
Arachidonoyl serotonin (N-arachidonoyl-serotonin AA-5-HT) is an endogenous lipid signaling molecule. It was first described in 1998 as being an inhibitor of fatty acid amide hydrolase (FAAH). In 2007 it was shown to have analgesic properties and to act as an antagonist of the TRPV1 receptor. In 2011 it was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion.
