Tags: Chemical Compound, Chemical Substance.
AP5 or APV ((2R)-amino-5-phosphonovaleric acid; (2R)-amino-5-phosphonopentanoate) is a selective NMDA receptor antagonist that competitively inhibits the ligand (glutamate) binding site of NMDA receptors.AP5 blocks the cellular analog of classical conditioning in the sea slug Aplysia californica and has similar effects on Aplysia long-term potentiation since NMDA receptors are required for both.
