Tags: Chemical Compound, Chemical Substance.
AP26113 is an investigational small-molecule targeted cancer therapy being developed by ARIAD Pharmaceuticals Inc. AP26113 has exhibited activity as a potent dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). This compound targets a unique genetic feature of cancer cells and ARIAD has begun a Phase 1/2 clinical trial of AP26113 based on patients’ molecular diagnoses in September 2011.