Tags: Drug.
AM-1714 is a drug that acts as a reasonably selective agonist of the peripheral cannabinoid receptor CB2 with sub-nanomolar affinity and 490x selectivity over the related CB1 receptor. In animal studies it has both analgesic and anti-allodynia effects. The 9-methoxy derivative AM-1710 has similar CB2 affinity but only 54x selectivity over CB1.
