Tags: Protein.
AP-2 complex subunit alpha-1 is a protein that in humans is encoded by the AP2A1 gene.This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP2 adaptors) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta) a medium adaptin (mu) and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles.