Tags: Chemical Compound, Chemical Substance.
Acylfulvene is a class of cytotoxic semi-synthetic derivatives of illudin a natural product that can be extracted from the jack o’lantern mushroom (Omphalotus olearius). One important acylfulvene 6-hydroxymethylacylfulvene (irofulven) has been evaluated for the treatment of a wide assortment of cancers and tumors. It is thought that acylfulvene compounds kill cancer cells by DNA alkylation (see DNA methylation).
