Tags: Disease.
Acute intermittent porphyria (AIP) is a rare autosomal dominant metabolic disorder affecting the production of heme the oxygen-binding prosthetic group of hemoglobin. It is characterized by a deficiency of the enzyme porphobilinogen deaminase. Acute intermittent porphyria is the second most common form of porphyria (porphyria cutanea tarda being the most common).