Tags: Enzyme.
In enzymology an acetoacetate-CoA ligase (EC 6.2.1.16) is an enzyme that catalyzes the chemical reactionATP + acetoacetate + CoA AMP + diphosphate + acetoacetyl-CoAThe 3 substrates of this enzyme are ATP acetoacetate and CoA whereas its 3 products are AMP diphosphate and acetoacetyl-CoA.This enzyme belongs to the family of ligases specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is acetoacetate:CoA ligase (AMP-forming).