Tags: Drug.
A-836339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective for CB2 with Ki values of 0.64nM at CB2 vs 270nM at the psychoactive CB1 receptor but while it exhibits selective analgesic anti-inflammatory and anti-hyperalgesic effects at low doses its high efficacy at both targets results in typical cannabis-like effects appearing at higher doses despite its low binding affinity for CB1.
