Tags: Drug.
A-412997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype with significantly improved selectivity over older D4-preferring compounds such as PD-168077 and CP-226269. In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate but without producing place preference or other signs of abuse liability.