Tags: Chemical Compound, Chemical Substance.

56-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) is a chemical compound that inhibits transcription elongation by RNA Polymerase II. Sensitivity to DRB is dependent on DRB sensitivity inducing factor (DSIF) negative elongation factor (NELF) and positive transcription elongation factor b (P-TEFb). DRB is a nucleoside analog and also inhibits some protein kinases.

Dichlororibofuranosylbenzimidazole.png
IUPAC name
(2R3R4S5R)-2-(56-Dichlorobenzimidazol-1-yl)-5-(hydroxymethyl)oxolane-34-diol

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