Tags: Protein.
The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine 5-HT) The 5-HT7 receptor is coupled to Gs (stimulates the production of the intracellular signaling molecule cAMP) and is expressed in a variety of human tissues particularly in the brain the gastrointestinal tract and in various blood vessels. This receptor has been a drug development target for the treatment of several clinical disorders.