Tags: Enzyme.
In enzymology a 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.60) is an enzyme that catalyzes the chemical reaction5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H+The 3 substrates of this enzyme are 5-carboxymethyl-2-hydroxymuconate semialdehyde H2O and NAD+ whereas its 3 products are 5-carboxymethyl-2-hydroxymuconate NADH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor.