Tags: Enzyme.
In enzymology a 4-hydroxyphenylacetate 1-monooxygenase (EC 1.14.13.18) is an enzyme that catalyzes the chemical reaction4-hydroxyphenylacetate + NAD(P)H + H+ + O2 homogentisate + NAD(P)+ + H2OThe 5 substrates of this enzyme are 4-hydroxyphenylacetate NADH NADPH H+ and O2 whereas its 4 products are homogentisate NAD+ NADP+ and H2O.This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen.