Tags: Enzyme.
In enzymology a 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) is an enzyme that catalyzes the chemical reaction4-hydroxymuconic semialdehyde + NAD+ + H2O maleylacetate + NADH + 2 H+The 3 substrates of this enzyme are 4-hydroxymuconic semialdehyde NAD+ and H2O whereas its 3 products are maleylacetate NADH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor.