Tags: Enzyme.
4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2 isopentenyl-diphosphate:NADP+ oxidoreductase LytB (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase HMBPP reductase IspH LytB/IspH) is an enzyme in the non-mevalonate pathway. It acts upon (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (or HMB-PP).