Tags: Enzyme.
In enzymology a 4-coumarate-CoA ligase (EC 6.2.1.12) is an enzyme that catalyzes the chemical reactionATP + 4-coumarate + CoA AMP + diphosphate + 4-coumaroyl-CoAThe 3 substrates of this enzyme are ATP 4-coumarate and CoA whereas its 3 products are AMP diphosphate and 4-coumaroyl-CoA.This enzyme belongs to the family of ligases to be specific those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 4-coumarate:CoA ligase (AMP-forming).