Tags: Enzyme.
In enzymology a 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase (EC 1.2.1.45) is an enzyme that catalyzes the chemical reaction4-carboxy-2-hydroxy-ciscis-muconate 6-semialdehyde + NADP+ + H2O 4-carboxy-2-hydroxy-ciscis-muconate + NADPH + 2 H+The 3 substrates of this enzyme are 4-carboxy-2-hydroxy-ciscis-muconate 6-semialdehyde NADP+ and H2O whereas its 3 products are 4-carboxy-2-hydroxy-ciscis-muconate NADPH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor.