3′-Phosphoadenosine-5′-phosphosulfate is a derivative of adenosine monophosphate that is phosphorylated at the 3′ position and has a sulfate group attached to the 5′ phosphate. This anion abbreviated PAPS is the most common coenzyme in sulfotransferase reactions. A related anion is adenosine 5′-phosphosulfate (APS) which is not phosphorylated at the 3′ position.
