Tags: Chemical Compound, Chemical Substance.
3-Methoxytyramine (3-MT) also known as 3-methoxy-4-hydroxyphenethylamine is a metabolite of the neurotransmitter dopamine formed by the introduction of a methyl group to dopamine by the enzyme catechol-O-methyl transferase (COMT). 3-MT can be further metabolized by the enzyme monoamine oxidase (MAO) to form homovanillic acid (HVA) which is then typically excreted in the urine.Originally thought to be physiologically inactive 3-MT has recently been shown to act as an agonist of the TAAR1.