Tags: Enzyme.
3-Isopropylmalate dehydrogenase (EC 1.1.1.85) is an enzyme that catalyzes the chemical reactions(2R3S)-3-isopropylmalate + NAD+ 4-methyl-2-oxopentanoate + CO2 + NADH(2R3S)-3-isopropylmalate + NAD+ (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH(2S)-2-isopropyl-3-oxosuccinate + H+ 4-methyl-2-oxopentanoate + CO2