Tags: Chemical Compound, Chemical Substance.

25-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine is a metabolite in the purine metabolism formed by the hydrolysis of GTP by GTP cyclohydrolase II. Alternatively two separate enzymes can carry out this reaction initially GTP cyclohydrolase IIa hydrolyses the 89 bond to form 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one followed by de-formylation by 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase.

25-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one.svg
IUPAC name
[(2R3S4R5R)-5-[(25-diamino-4-oxo-1H-pyrimidin-6-yl)amino]-34-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

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