Tags: Enzyme.
In enzymology a 2-hydroxymethylglutarate dehydrogenase (EC 1.1.1.291) is an enzyme that catalyzes the chemical reaction(S)-2-hydroxymethylglutarate + NAD+ 2-formylglutarate + NADH + H+Thus the two substrates of this enzyme are (S)-2-hydroxymethylglutarate and NAD+ whereas its 3 products are 2-formylglutarate NADH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.