Tags: Chemical Compound, Chemical Substance.
2-Aminoethoxydiphenyl borate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1 TRPV2 & TRPV3 at higher concentrations). In research it is used to manipulate intracellular release of calcium ions (Ca2+) and modify TRP channel activity although there its lack of specific effects make it less than ideal under some circumstances.