Tags: Enzyme.
In enzymology a 15-hydroxyprostaglandin-I dehydrogenase (NADP+) (EC 1.1.1.231) is an enzyme that catalyzes the chemical reaction(5Z13E)-(15S)-69alpha-epoxy-11alpha15-dihydroxyprosta-513- dienoate + NADP+ (5Z13E)-69alpha-epoxy-11alpha-hydroxy-15-oxoprosta-513-dienoate + NADPH + H+The 3 substrates of this enzyme are (5Z13E)-(15S)-69alpha-epoxy-11alpha15-dihydroxyprosta-513- dienoate and NADP+ whereas its 3 products are (5Z13E)-69alpha-epoxy-11alpha-hydroxy-15-oxoprosta-513-dienoate NADPH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.