Tags: Drug.
14-Cinnamoyloxycodeinone is the most potent example in a series of opiate analgesic drugs discovered in the 1960s with > ×100 times the potency of morphine. It is a derivative of hydroxycodeinone being the 14-cinnamate ester. In another paper Buckett assigns the potency as 177 with a range (depending on animal and test) of ×101 – ×310. It may be of interest to researchers that the allyl group in this compound and in allylprodine overlay very closely.
