Tags: Chemical Compound, Chemical Substance.
10-Formyltetrahydrofolate (10-CHO-THF) is form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-CHO-THF is used as a substrate in formyltransferase reactions. This is important in purine biosynthesis where 10-CHO-THF is a substrate for phosphoribosylaminoimidazolecarboxamide formyltransferase as well as in the formylation of the methionyl initiator tRNA (fMet-tRNA) when 10-CHO-THF is a substrate for methionyl-tRNA formyltransferase.
