List of articles in "Drug" category - Page 7

SGN-CD19A is an antibody-drug conjugate (ADC) directed to CD19 designed for the treatment of CD19-positive acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma. It consists of an anti-CD19 mAb linked to […]

SGN-CD33A is an antibody-drug conjugate (ADC) directed to CD33 designed for the treatment of Acute myeloid leukemia. It consists of a humanized anti-CD33 mAb with 2 engineered cysteine residues. The […]

cBR96-doxorubicin immunoconjugate (BMS-182248/SGN-15) was an antibody-drug conjugate (ADC) directed to the Lewis-Y antigen designed for the treatment of cancer. The payload was doxorubicin which was connected with a hydrazone linker […]

Otlertuzumab is a humanized monoclonal antibody designed for the treatment of cancer.This drug was developed by Emergent BioSolutions.

Aducanumab is a human monoclonal antibody designed for the treatment of Alzheimer’s disease.This drug was developed by Biogen Idec Inc.

Technetium (99mTc) etarfolatide is an investigational non-invasive folate receptor-targeting companion imaging agent that is being developed by Endocyte. Etarfolatide consists of a small molecule targeting the folate receptor and an […]

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Befol). It is a non-competitive reversible inhibitor of monoamine oxidase A that […]

Prostaglandin E3 (PGE3) is a naturally formed prostaglandin and is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.

Alstonine is an indole alkaloid and putative antipsychotic constituent of various plant species including Alstonia boonei Catharanthus roseus Picralima nitida Rauwolfia caffra and Rauwolfia vomitoria. In preclinical studies alstonine attenuates […]

Methoxphenidine (MXP) or (1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine) is a chemical that acts as an NMDA receptor channel blocker and is currently sold as a designer drug. Its pharmacology in humans has not been […]