Tenofovir alafenamide fumarate (TAF) (formerly GS-7340) is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment […]
List of articles in "Drug" category - Page 54
Epristeride
Epristeride (SKF-105657 ONO-9302) is a selective transition state non-competitive inhibitor of the type II isoform of the enzyme 5α-reductase similarly to finasteride and turosteride. It was under development for the […]
Mitratapide
Mitratapide is a veterinary drug for the treatment of overweight and obese dogs sold under the brand name Yarvitan. Its mechanism of action involves inhibition of microsomal triglyceride transfer protein […]
UR-144
UR-144 (TMCP-018 KM-X1 MN-001 YX-17) is a drug invented by Abbott Laboratories that acts as a selective full agonist of the peripheral cannabinoid receptor CB2 but with much lower affinity […]
Olodaterol
Olodaterol (trade name Striverdi) is a long acting beta-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD) manufactured by Boehringer-Ingelheim.
MDA-19
MDA-19 is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB2 with reasonable selectivity over the psychoactive CB1 receptor though with some variation between […]
Lumacaftor
Lumacaftor (USAN codenamed VX-809) is an experimental drug for the treatment of cystic fibrosis being developed by Vertex Pharmaceuticals. The drug is designed to be effective in patients that have […]
3-Monoacetylmorphine
3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine) the other two being morphine and more active 6-monoacetylmorphine (6-MAM).Because of the acetyl-group in 3-position 3-MAM has relatively […]
Suvorexant
Suvorexant (MK-4305) is a dual orexin receptor antagonist in development by Merck & Co. for the treatment of insomnia. It is not currently approved for commercial use but it has […]
Cantuzumab ravtansine
Cantuzumab ravtansine is a humanized monoclonal antibody designed for the treatment of cancers. The antibody cantuzumab is linked to a cytotoxic agent ravtansine.