Norbuprenorphine is the primary active metabolite of buprenorphine. Norbuprenorphine acts as a μ-opioid δ-opioid and nociceptin receptor full agonist as well as a κ-opioid receptor partial agonist. Norbuprenorphine crosses the […]
List of articles in "Drug" category - Page 443
Butamben
Butamben is a local anesthetic. It is the ester of 4-aminobenzoic acid and butanol.
Eplerenone
Eplerenone (INN) /ɛpˈlɛrənoʊn/ is an aldosterone antagonist used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone though it is much more […]
Rifaximin
Rifaximin(Rifagut) is a semisynthetic antibiotic based on rifamycin. It has poor oral bioavailability meaning that very little of the drug will be absorbed into the blood stream when it is […]
Loprazolam
Loprazolam (Triazulenone) marketed under the brand names Dormonoct Havlane Sonin Somnovit is a drug which is an imidazole benzodiazepine derivative. It possesses anxiolytic anticonvulsant sedative and skeletal muscle relaxant properties. […]
Tenofovir/emtricitabine
Tenofovir/emtricitabine trademark Truvada® by Gilead Sciences is a fixed-dose combination of two antiretroviral drugs used for the treatment of HIV. It consists of 300 milligrams of tenofovir disoproxil fumarate (of […]
Pramipexole
Pramipexole (Mirapex Mirapexin Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson’s disease (PD) and restless legs syndrome (RLS).
SB-649868
SB-649868 is an orexin receptor antagonist in development by GlaxoSmithKline. Currently in Phase 2 development this drug for sleep disorders is one of two such compounds currently in development the […]
Guanfacine
Guanfacine (brand name Tenex and the extended release Intuniv) is a sympatholytic. It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the […]