Reslizumab is a humanized monoclonal antibody intended for the treatment of eosinophil-meditated inflammations of the airways skin and gastrointestinal tract. As of September 2009 the drug is undergoing Phase II/III […]
List of articles in "Drug" category - Page 371
Pexelizumab
Pexelizumab is a drug designed to reduce side effects of coronary artery bypass grafting and angioplasty among other types of cardiac surgery. It is a single chain variable fragment of […]
Pascolizumab
Pascolizumab is a humanized monoclonal antibody for the treatment of asthma. A Phase II clinical trial in patients with symptomatic glucocorticoid naive asthma has been conducted in 2001/2002.
Ocrelizumab
Ocrelizumab is a humanized anti-CD20 monoclonal antibody. It targets mature B lymphocytes and hence is an immunosuppressive drug candidate. It is under development by Hoffmann–La Roche’s subsidiary Genentech and Biogen […]
Fontolizumab
Fontolizumab (planned trade name HuZAF) is a humanized monoclonal antibody and an immunosuppressive drug for the treatment of auto-immune diseases like Crohn’s disease. A phase II clinical trial investigating the […]
Erlizumab
Erlizumab also known as rhuMAb is a recombinant humanized monoclonal antibody that was an experimental immunosuppressive drug. Erlizumab was developed by Genentech under a partnership with Roche to treat heart […]
Tremelimumab
Tremelimumab (formerly ticilimumab CP-675206) is a fully human IgG2 monoclonal antibody produced by Pfizer undergoing human trials for the treatment of cancer. Cytotoxic T lymphocytes (CTLs) can recognize and destroy […]
Vapaliximab
Vapaliximab is a chimeric monoclonal antibody and an immunosuppressive drug.[citation needed]
Teneliximab
Teneliximab is a chimeric monoclonal antibody binding to the immune stimulatory protein CD40. As of 2009 it has not entered clinical trials.
Lumiliximab
Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator and as of October 2009 it is being investigated in Phase I and II clinical trials for […]