List of articles in "Drug" category - Page 121

Ezlopitant (CJ-11974) is an NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome but it appears to have been […]

Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed. It acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist. In addition to […]

Cinitapride (Cintapro Pemix) is a gastroprokinetic agent and antiulcer agent of the benzamide class which is marketed in India Mexico Pakistan and Spain. It acts as an agonist of the […]

Caroxazone (Surodil Timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed. It acts as a reversible monoamine oxidase inhibitor (MAOI) […]

Echinopsidine (Adepren) is an antidepressant that was under development in Bulgaria for the treatment of depression. It increases serotonin norepinephrine and dopamine levels in the brain and is believed to […]

Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A) thereby being a RIMA and to a lesser extent semicarbazide-sensitive amine oxidase (SSAO) as well as a serotonin releasing […]

Pipofezine (Azafen or Azaphen) is a tricyclic antidepressant (TCA) approved in Russia for the treatment of depression. It was introduced in the late 1960s and is still used today.Pipofezine has […]

Trioxifene (LY-133314) is a selective estrogen receptor modulator (SERM) with competitive binding activity against estradiol for estrogen receptor alpha (ERalpha) and antagonistic activity against ERalpha-mediated gene expression. It has demonstrated […]

Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen. It is used as a powder-and-solvent injection kit for the treatment for Dupuytren’s contracture a […]

Pirandamine (AY-23713) is a tricyclic derivative which acts as a selective serotonin reuptake inhibitor (SSRI). It was investigated in the 1970s as a potential antidepressant but clinical development wasn’t commenced […]