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List of articles in "Drug" category - Page 12

Ethacizine

Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and […]


Acetylcysteinamide

N-Acetylcysteine amide (abbrev. NACA AD4 and also known as acetylcysteinamide) is a recently synthesised amide derivative of N-acetylcysteine that appears to have better blood-brain barrier permeability and bioavailability and a […]


SR9011

SR9011 is a research drug that was developed by Professor Thomas Burris of Scripps as an agonist of Rev-ErbAαwith a half-maximum inhibitory concentration (IC50) = 790 nM for Rev-Erbα and […]


SR9009

SR9009 is a research drug that was developed by Professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA (i.e. increases the constitutive repression of genes regulated […]


Brilacidin

Brilacidin (formerly PMX-30063) is an antibiotic that works by disrupting bacterial cell membranes mimicking defensins from innate immunity.


Bimagrumab

Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20 2013 it was announced that bimagrumab was granted breakthrough therapy […]


Cobimetinib

Cobimetinib (GDC-0973 XL-518) is a MEK inhibitor being developed by Exelixis and Roche. It is being studied in combination with vemurafenib to treat several cancers including melanoma.


Tideglusib

Tideglusib (NP-12 NP031112) is a potent selective and irreversible small molecule non-ATP-competitive GSK3 inhibitor that has been investigated as a potential treatment for Alzheimer’s disease and paralysis supranuclear palsy in […]


4-HTMPIPO

4-HTMPIPO is a synthetic cannabinoid drug first identified in smoking products purchased from online vendors in 2012. 4-HTMPIPO is the product resulting from the electrophilic addition of water to the […]


Pyrazolam

Pyrazolam is a benzodiazepine derivative originally developed by a team lead by Leo Sternbach at Hoffman-La Roche in the 1970s and subsequently rediscovered and sold as a research chemical starting […]


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